Tuesday, September 1, 2015

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Product details

File Size: 1270 KB

Print Length: 265 pages

Publisher: Johns Hopkins University Press; 1 edition (November 13, 2014)

Publication Date: November 13, 2014

Sold by: Amazon Digital Services LLC

Language: English

ASIN: B00OY5ENKK

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Amazon Best Sellers Rank:

#1,659,075 Paid in Kindle Store (See Top 100 Paid in Kindle Store)

Good book.

This book has some interesting parts dealing with the history of the discovery of autoimmunity, and it is competently although not engagingly written. It is pretty scant on details regarding the pathology, or even the specific molecular markers and targets of the many diseases. It is also disappointing that the work of several luminaries is dismissed without much discussion of what they actually proposed. For example, the lack of discussion of Jerne, who won the Nobel Prize for his work, which was highly respected at the time but now is thought not really relevant to the understanding of Immunology. Amusingly, the authors refer to the work of Gadjusek in complement fixation, then dismissively state he went on to propose some vague genetic explanation for Kuru, a disease in a native tribe in New Guinea. Whether one respects what he found or not, it did win the Nobel Prize, and it was not a vague genetic disease, but appeared to be a slow virus that was transmitted through cannibalism. The final section of the book is a waste of time. It attempts to inject philosophy into the self- not-self question. This was pure sophistry. Finally, the book proper is actually less than half the total pages, which include a very extensive bibliography and index. The bibliography stands alone, as the cited works are not referenced in the text. Most curious.

A must read for anyone interested in the history of immunology - beautifully written

In his latest book Anderson (along with McKay) again brilliantly straddles the chasm that often exists between science and the public understanding of it. By making disease both deeply personal and yet retaining a narrative that is both scientifically literate and philosophically stimulating he again pulls of a remarkable feat-a book that thoroughly satisfies the expert and lay person. I loved his book on kuru for the same reasons. A must read for a wide range of intelligent minds.

This book makes a uniquely wonderful, learned and readily readable contribution to the medical, scientific, historical, social and literary underpinnings of autoimmunity and its discontents, and will keep the reader's attention and improve his or her knowledge throughout. I highly commend it to both the specialist and general reader.

nice read. Interesting topic

I was looking forward to reading this book because I like immunology. I was very disappointed. The language is stilted and there is too much philosophy and not enough immunology. There is very little information about the scientists as people. While the book started slowly, I was hoping that it would improve or that I would get more used to the authors' style as I progressed through the book. Alas this didn't happen and I stopped reading the book about halfway through. I cannot recommend this book.

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